Abdominal compartment syndrome in neutropenic enterocolitis

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Abdominal compartment syndrome

Intra-abdominal hypertension (IAH) associated with organ dysfunction defines the abdominal compartment syndrome (ACS). Elevated intra-abdominal pressure (IAP) adversely impacts pulmonary, cardiovascular, renal, splanchnic, musculoskeletal/integumentary, and central nervous system physiology. The combination of IAH and disordered physiology results in a clinical syndrome with significant morbidi...

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Abdominal compartment syndrome is a potentially lethal condition caused by any event that produces intra-abdominal hypertension; the most common cause is blunt abdominal trauma. Increasing intraabdominal pressure causes progressive hypoperfusion and ischemia of the intestines and other peritoneal and retroperitoneal structures. Pathophysiological effects include release of cytokines, formation ...

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Various systems are involved in this syndrome. First, the increased intra-abdominal pressure is transmitted to the pleural space so that lung compliance decreases. Hypoventilation and alteration of ventilation/perfusion distribution lead to hypoxemia and hypercapnia. When mechanical ventilation is applied, very high inspiratory pressures are often required to deliver tidal volume. Second, the c...

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As per definition Abdominal Compartment Syndrome (ACS) is the sudden increase in the Intra-Abdominal pressure resulting in alteration in the respiratory mechanism, hemodynamic parameters, and renal as well as cerebral perfusion. ACS has tremendous relevance in the practice of surgery and the care of critically ill patients, because of its effects on multiple organ systems. Typically the patient...

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ژورنال

عنوان ژورنال: British Journal of Haematology

سال: 2012

ISSN: 0007-1048

DOI: 10.1111/bjh.12140